Efficacy of the Five-Element Music Therapy Combined with Mindfulness Meditation on the Fatigue, Anxiety and Depression of Diffuse Large B-Cell Lymphoma Patients Who Are Undergoing Chemotherapy.
Tao Chen, Haolei Niu, Yan Wang
Noise and Health DOI: 10.4103/nah.nah_145_25 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Retrospective study Peer reviewed |
|---|---|
| Sample size | 78 |
| Population | Diffuse large B-cell lymphoma patients undergoing chemotherapy |
| Interventions | Five-element music therapy Mindfulness meditation |
| Topics | Anxiety Depression Meditation |
| Keywords | Fatigue Mindfulness meditation Music therapy |
| Key points | Five-element music therapy combined with mindfulness meditation reduces cancer-related fatigue, anxiety, and depression while improving sleep, treatment compliance, and quality of life in DLBCL chemotherapy patients. |
Abstract
Patients with diffuse large B-cell lymphoma (DLBCL) frequently experience cancer-related fatigue (CRF), anxiety and depression during chemotherapy, significantly impairing their quality of life. This study evaluates the efficacy of the five-element music therapy combined with mindfulness meditation in alleviating CRF and psychological distress amongst DLBCL patients who are undergoing chemotherapy. We conducted a retrospective study on 78 DLBCL patients who were treated at the First Affiliated Hospital of Soochow University (June 2022-December 2023). The patients were divided as follows: (1) conventional care group (n = 39) and (2) conventional care + combined five-element music therapy and mindfulness meditation group (combined group, n = 39). The assessed outcomes included the following: Cancer Fatigue Scale, Pittsburgh Sleep Quality Index (PSQI), the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), the Hamilton Depression (HAMD) and Hamilton Anxiety (HAMA) scales, treatment compliance and nursing satisfaction scores. Compared with the conventional care group, the combined group had lower scores in physical fatigue, emotional fatigue and cognitive fatigue (all P < 0.001); lower scores in HAMD, HAMA and PSQI (all P < 0.001); longer sleep duration (P < 0.001); better compliance (P = 0.023); higher satisfaction (P = 0.042) and a higher score in EORTC QLQ-C30 (all P < 0.001). The combination of the five-element music therapy with mindfulness meditation reduces CRF, anxiety and depression amongst DLBCL chemotherapy patients whilst enhancing treatment compliance, sleep quality and overall quality of life. This combined non-pharmacological approach demonstrates promise as an adjunctive therapy in oncology care.
Comparable studies
Other observational and cohort studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia | 1992 | Observational cohort | n = 22 |
| Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder | 2015 | Observational study | |
| Patterning of Cognitive and Somatic Processes in the Self-Regulation of Anxiety: Effects of Meditation versus Exercise Regular practitioners of physical exercise or meditation | 1978 | Retrospective study | n = 77 |
| Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans | 2020 | Observational study | |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
Citations in the library
Cites 4
- A mindfulness meditation mobile app improves depression and anxiety in adults with sleep disturbance: Analysis from a randomized controlled trial General Hospital Psychiatry September 11, 2021
- Exploring Influencing Factors of Anxiety Improvement Following Mindfulness-Based Music Therapy in Young Adults with Cancer. Journal of Music Therapy June 1, 2023
- The effects of mindfulness-based interventions on symptoms of depression, anxiety, and cancer-related fatigue in oncology patients: A systematic review and meta-analysis PLoS One July 14, 2022
- Effect of mindfulness yoga on anxiety and depression in early breast cancer patients received adjuvant chemotherapy: a randomized clinical trial Journal of Cancer Research and Clinical Oncology July 5, 2022