Exploring new frontiers: Effects of psychedelics on neurotransmitter‐regulated glucagon release in pancreatic islets
Diabetes, Obesity & Metabolism December 14, 2023 DOI: 10.1111/dom.15411 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Commentary Peer reviewed |
|---|---|
| Keywords | Glucagon Diabetes mellitus Library science Endocrinology |
| Key points | Proposes that psychedelics may alter neurotransmitter concentrations involved in signaling pathways that regulate glucagon release from pancreatic alpha cells. |
Abstract
Research on psychedelic substances such as lysergic acid diethylamide (LSD), psilocybin, and dimethyltryptamine (DMT) is gaining momentum.1 However, the possible effects of these substances on systemic functions such as endocrine activity, particularly neurotransmitter-regulated glucagon release in pancreatic alpha cells, remain largely unexplored. This commentary aims to address the unprecedented subject of how psychedelics might alter neurotransmitter concentrations involved in both intra-islet and extra-islet signalling, thereby impacting glucagon release. [...]
Citations in the library
Cites 3
- Psychedelics Promote Structural and Functional Neural Plasticity Cell Reports June 1, 2018
- Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms Pharmacological Reviews December 16, 2020
- The neurobiology of psychedelic drugs: implications for the treatment of mood disorders. Nature Reviews Neuroscience September 2010