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Psychedelic pathways: Exploring reinforcement learning under psychedelic influence

Federico Cavanna, Enzo Tagliazucchi

Open Science Framework 2025 DOI: 10.17605/osf.io/52hxf (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Placebo-controlled Double-blind Peer reviewed
Population Healthy adults
Intervention Psilocybin
Topics Psilocybin
Keywords Cognitive psychology Reinforcement learning Neural activity Electroencephalography
Key findings Psilocybin modulates neural mechanisms of reward processing and decision-making during probabilistic reinforcement learning.

Abstract

This project investigates the acute effects of psilocybin on probabilistic reinforcement learning in healthy adults. Using a double blind, randomized, within-subject, placebo-controlled design, we will analyze behavioral data and Event-Related Potentials (ERPs) from EEG recordings to understand how psychedelics modulate neural mechanisms of reward processing and decision-making.

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