Mathematical proof of the Fisher-Escolà Q statistical distribution in quantum consciousness modeling.
Álex Escolà-Gascón, Julián Benito-León
Computational and Structural Biotechnology Journal 2025 DOI: 10.1016/j.csbj.2025.04.025 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical and simulation study Peer reviewed |
|---|---|
| Sample size | 150 |
| Population | Density matrices of entangled states in a 10-qubit quantum system |
| Keywords | Hypothesis testing Q fisher-escolà distribution Quantum fisher information Quantum consciousness Quantum entanglement Quantum-consciousness Mathematical-physics Quantum-entanglement Neuroscience-research Statistical-analysis |
| Citations | 5 |
| Key points | Introduces the Q of Fisher-Escolà distribution, a statistical model integrating quantum and classical probabilities, mathematically confirmed to follow a beta distribution, enabling empirical hypothesis testing in consciousness research. |
Abstract
Quantum theories have long sought to explain conscious experience, yet their biggest challenge is not conceptual but methodological. A critical gap remains: the lack of statistical tools capable of empirically testing these theories against objective reality. This study introduces and formalizes the Q of Fisher-Escolà distribution, the first statistical model to integrate quantum and classical probabilities, enabling robust inferential analysis in neuroscience and consciousness studies. We examined 150 density matrices of entangled states in a 10-qubit quantum system using IBM's quantum supercomputers. Through maximum likelihood estimation, we mathematically confirmed that Q Fisher-Escolà ∼ beta(a, b, loc, scale). As a key contribution, a novel analytical solution to the Quantum Fisher Information (QFI) integral was derived, improving decoherence stability. Additionally, 10⁵ Monte Carlo simulations allowed us to establish critical thresholds for α = 0.05, 0.01, 0.001, and 0.0001, while assessing Type I and II error rates. Type I errors appeared in 2-5 % of right-tailed tests at α = 0.05 but approached zero as α decreased. Type II errors occurred in left-tailed tests (1-4 % at α = 0.05) but also diminished with stricter significance levels. In two-tailed tests, both error types remained below 3 %, highlighting the distribution's robustness. The Q of Fisher-Escolà distribution pioneers a statistical framework for modeling quantum-classical interactions in consciousness research. It enables hypothesis testing and predicting subjective experiences, with applications in neuroscience and computational automation. Supported by mathematical proofs and empirical validation, this model advances the integration of quantum probability into neuroscience.
Citations in the library
Cited by 3
- Brain entangled quantum states in radical pairs: a possible link to consciousness. Brain Research June 8, 2026
- EMI model: A scale free biophysical framework for human consciousness, cognition and behaviour. Biosystems January 2026
- Beyond the brain: a computational MRI-derived neurophysiological framework for robotic conscious capacity. Neuroscience & Biobehavioral Reviews December 1, 2025
Cites 10
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and 5 more in the library