Psilocybin‐assisted therapy reduces heavy drinking in patients with AUD
The Brown University Psychopharmacology Update November 3, 2022 DOI: 10.1002/pu.30946 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Population | Patients with alcohol use disorder |
| Topics | Addiction Psilocybin |
| Keywords | Adverse effect Placebo Hallucinogen Randomized controlled trial Psychotherapist Pharmacology Alternative medicine |
| Key findings | Two sessions of psilocybin-assisted psychotherapy reduced heavy-drinking days and other alcohol-related problems compared to placebo plus psychotherapy. |
Abstract
Two sessions of psilocybin‐assisted psychotherapy resulted in reduced heavy‐drinking days and other alcohol‐related problems relative to placebo plus psychotherapy in a randomized trial involving patients with alcohol use disorder (AUD). There were no serious adverse events associated with psilocybin administration, and no signs of psychotic disturbances. Study results were published online Aug. 24, 2022, in JAMA Psychiatry .
Comparable studies
Other randomized controlled trials on psilocybin for addiction, most cited first.