Psilocybin treatment for AUD: Promise in new study
Alcoholism & Drug Abuse Weekly October 14, 2022 DOI: 10.1002/adaw.33584 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Population | Individuals with alcohol use disorder |
| Topics | Addiction LSD Psilocybin |
| Keywords | Hallucinogen Psychotherapist |
| Key findings | Psilocybin-assisted psychotherapy has significant beneficial effects on alcohol use disorder. |
Abstract
The beneficial effects of psilocybin‐assisted psychotherapy on alcohol use disorder (AUD) are significant, based on a study published in JAMA Psychiatry last month. In general, psychedelic medications have been a focus of research, but less is known about psilocybin, and it has been 40 years since the studies with lysergic acid diethylamide (LSD) provided double the remissions as comparison treatments.
Comparable studies
Other randomized controlled trials on LSD for addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| MDLSD: study protocol for a randomised, double-masked, placebo-controlled trial of repeated microdoses of LSD in healthy volunteers Healthy male participants | 2021 | Randomized controlled trial | n = 80 |
| 720. Unraveling anxiolytic and anti-addictive properties of lysergic acid diethylamide in a model of alcohol use disorder Adults aged 18 to 74 years with a primary diagnosis of moderate to severe generalized... | 2026 | Phase 2b, multicenter, randomized, double-blind, placebo-controlled trial | n = 198 |