Exploring the Impact of Recreational Drugs on Suicidal Behavior: A Narrative Review
Rosa María Moret, Sergio Sanz‐gómez, Santiago Gascón, Adrián Alacreu‐crespo
Psychoactives July 3, 2024 DOI: 10.3390/psychoactives3030021 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Narrative review Peer reviewed |
|---|---|
| Topics | Addiction Cannabis MDMA Psilocybin |
| Keywords | Hallucinogen Recreational drug Methamphetamine Recreational use Heroin Substance abuse Nicotine Clinical psychology |
| Citations | 4 |
| Key findings | All examined recreational drugs appear to have a deleterious effect on suicidal behavior except for ketamine and psilocybin, which may confer a protective effect. |
Abstract
Substance use/abuse and suicide are two closely related phenomena, mostly due to neurobiological, psychological, and social impairments. In the present narrative review, the relationship between suicidal behavior (SB) and the use and abuse of common recreational drugs, such as alcohol, cannabis, cocaine, methamphetamine, heroin, nicotine, ketamine, psilocybin, MDMA, and LSD, has been explored. Furthermore, potential mechanisms linking the two have also been examined. According to current research, all substances appear to have a deleterious effect on SB except for ketamine and psilocybin, which could potentially confer a protective effect. Further studies are needed to understand the relationship between MDMA, LSD, and suicide.
Comparable studies
Other narrative reviews on MDMA for addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants | 2016 | Review | |
| Methamphetamine and MDMA (Ecstasy) Neurotoxicity: 'of Mice and Men' | 2004 | Review | |
| Use and abuse of dissociative and psychedelic drugs in adolescence Adolescent humans and preclinical animal models | 2021 | Review | |
| Can MDMA Play a Role in the Treatment of Substance Abuse? | 2013 | Review | |
| Neuroimaging in Human MDMA (Ecstasy) Users | 2008 | Review |
Citations in the library
Cites 20
- Global Street Food: la cocina de la calle Diseño interior 2009
- Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. Journal of Psychopharmacology March 1, 2015
- Psilocybin-Induced Decrease in Amygdala Reactivity Correlates with Enhanced Positive Mood in Healthy Volunteers Biological Psychiatry April 26, 2014
- Psychedelics not linked to mental health problems or suicidal behavior: A population study Journal of Psychopharmacology March 1, 2015
- Effects of serotonin 2A/1A receptor stimulation on social exclusion processing Proceedings of the National Academy of Sciences April 18, 2016
and 15 more in the library