Psychotropic Drug-Induced Transformations of Visual Space
International Pharmacopsychiatry 1971 DOI: 10.1159/000468248 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Humans |
| Interventions | Psilocybin D-amphetamine Chlorpromazine |
| Keywords | Drug Space punctuation Pharmacology |
| Citations | 7 |
| Key findings | Ergotropic arousal-inducing drugs interfere with counter-adaptation to optical distortion, while the trophotropic drug chlorpromazine promotes it. |
Abstract
It was found that ergotropic arousal-inducing drugs, such as psilocybin, a Ditran®-type 'glycolate' and D-amphetamine, significantly lower human spatial distortion thresholds, i.e. these drugs interfere with counter-adaptation to optical distortion, or the intention to see the world undistorted. The trophotropic arousal-inducing chlorpromazine®on the other hand promotes such counter-adaptation, i.e. the optimization of visual information. The interference with optimization is independent of the rate at which the distorting stimulus is presented. Optimization is regarded here as a cortical (perceptual-behavioral) interpretive process while interference with and promotion of the optimization are subcortical influences.