Psilocybin therapy: A novel approach to treating depression
Tooba Noor, Areej Shakil, Aimen Waqar Khan, Syeda Mahrukh Fatima Zaidi, Hussain Sohail Rangwala, Burhanuddin Sohail Rangwala
International Journal of Surgery Global Health June 2, 2023 DOI: 10.1097/gh9.0000000000000175 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Topics | Anxiety Depression Psilocybin |
| Keywords | Depression economics Suicidal ideation Mental health Antidepressant Medical prescription Pharmacotherapy Population Psychological intervention Suicide prevention Poison control Emergency medicine |
| Key points | States that depression affects roughly 280 million people globally (about 3.8%), that the COVID-19 pandemic has increased cases and antidepressant prescriptions, and that UK guidance recommends medication as first-line treatment for moderate to severe depression while noting its limitations and potential for unsatisfactory outcomes. |
Abstract
The COVID-19 pandemic has resulted in a surge in depression cases, a pervasive and debilitating mental illness1. This trend is evident in the increased prescriptions for antidepressants. Depression is a chronic condition that affects a significant proportion of the global population, with ~280 million people, or about 3.8%, suffering from it. As a result, it is a significant mental health concern worldwide2. The National Institute for Health and Care Excellence in the United Kingdom recommends medication as the primary treatment for individuals with moderate to severe depression. However, it has limitations and may yield unsatisfactory outcomes.
Citations in the library
Cites 10
- Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Scientific Reports October 13, 2017
- Increased global integration in the brain after psilocybin therapy for depression. Nature Medicine April 11, 2022
- Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up Journal of Psychopharmacology February 1, 2022
- Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Acta Psychiatrica Scandinavica October 30, 2020
- Taking Psychedelics Seriously Journal of Palliative Medicine January 22, 2018
and 5 more in the library