Psychedelics and Personality
Marc Aixalà, Rafael G. Dos Santos, Jaime E. C. Hallak, José Carlos Bouso
ACS Chemical Neuroscience June 4, 2018 DOI: 10.1021/acschemneuro.8b00237 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Anxiety Ayahuasca LSD Psilocybin Serotonin |
| Keywords | Hallucinogen Mood Clinical psychology |
| Citations | 14 |
| Key findings | Psychedelics show potential for treating mood, anxiety, and substance use disorders, but their mechanisms are not fully understood. |
Abstract
In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders. The mechanisms responsible for these effects are not fully understood but seem to involve changes in bran dynamics in areas rich in serotonergic 5-HT2A receptors and in personality. In the present text, we present a brief and critical overview of the current research in this field, pointing out both promises and limitations of these studies.
Comparable studies
Other narrative reviews on ayahuasca for anxiety, most cited first.