Poisoning by hallucinogenic mushroom Hikageshibiretake (Psilocybe argentipes K. Yokoyama) indigenous to Japan.
Morihiro Musha, Atsushi Ishii, Fumio Tanaka, Genjiro Kusano
The Tohoku Journal of Experimental Medicine 1986 DOI: 10.1620/tjem.148.73 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 5 |
| Population | Individuals poisoned by Psilocybe argentipes mushrooms |
| Topics | Anxiety Psilocybin |
| Keywords | Mushroom poisoning Hallucinogen Amnesia Panic Consciousness |
| Citations | 15 |
| Key findings | Poisoning by Psilocybe argentipes produces clinical features similar to pure psilocybin, including acute toxic stupor with amnesia, psychedelic states, and psychotic reactions with vivid hallucinations, all accompanied by anxiety and panic. |
Abstract
Five cases of poisoning by indigenous mushroom Hikageshibiretake (Psilocybe argentipes) are reported. As this mushroom contains psilocybin, in general, clinical features were similar to those seen by pure psilocybin. Acute toxic stuporous state with complete amnesia in the culminating period occurred in one case, psychedelic state with dreamy consciousness in one case and psychotic adverse reactions with vivid visual hallucinations with consciousness in three cases. There were accompanied with anxiety and panic reactions to subjective experiences. Though these toxic effects were usually short-lived, for management of such patients it is important to recognize that horrible emotional reactions and other harmful behavioral problems can also occur.
Comparable studies
Other case reports and case series on psilocybin for anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psilocybin and Obsessive Compulsive Disorder Individual with Obsessive Compulsive Disorder | 2014 | Case study | n = 1 |
| A suicide attempt following psilocybin ingestion in a patient with no prior psychiatric history 30-year-old male with no psychiatric history | 2023 | Case study | n = 1 |
| Self-treatment of depression and complex post-traumatic stress disorder with psilocybin and LSD—A retrospective case study Young man with early-onset complex trauma, anxiety, and depression | 2023 | Case study | n = 1 |
| Serotoninergic antidepressants combination in psilocybin-assisted psychotherapy: a case report Adult patient with difficult-to-treat depression | 2024 | Case report | n = 1 |
| Self-treatment of parental neglect-induced mixed anxiety and depressive disorder with psilocybin – A retrospective case study Young woman in her mid-twenties with a history of depression since childhood | 2023 | Case study | n = 1 |