Correction: Dissociable effects of psilocybin and escitalopram for depression on processing of musical surprises.
Rebecca Harding, Neomi Singer, Matthew B. Wall, Talma Hendler, David Erritzøe, David Nutt, Robin Carhart-Harris, Leor Roseman
Mol Psychiatry July 1, 2025 correction DOI: 10.1038/s41380-025-03066-1 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial |
|---|---|
| Topics | Psilocybin Psychedelic-assisted therapy Depression |
| Keywords | Depression treatment Mood improvement Mental health therapy Psychiatric treatment Therapeutic mechanisms Relief from depression Brain activity Brain processing Cognitive neuroscience Neural mechanisms Brain function Neurological study Psilocybin research Psilocybin effects Drug study Pharmacological research Escitalopram study Antidepressant research Auditory processing Musical cognition Musical surprises Unexpected events processing Sensory processing Auditory perception Musical note |
| Key findings | Psilocybin therapy decreased activation in the ventromedial prefrontal cortex and angular gyrus while increasing activation in sensory regions during processing of unexpected musical notes. |
Abstract
The following part of the abstract had a minor error: ‘Following PT, there was greater activation in the ventromedial prefrontal cortex and sensory regions, and reduced activation in the angular gyrus.’ This is now corrected to ‘Following PT, there was decreased activation in the ventromedial prefrontal cortex and angular gyrus, and greater activation in sensory regions.’ The original article has been updated accordingly.