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Leveraging psychedelic neuroscience to boost human creativity using artificial intelligence.

Brian M. Ross

Front Artif Intell June 4, 2025 DOI: 10.3389/frai.2025.1589086 (opens in new tab) via PubMed Central

Summary

AI-generated from the abstract

LSD and psilocybin disrupt rigid cognitive patterns, likely by altering Default Mode Network activity, reducing latent inhibition, increasing divergent thinking, and promoting implicit learning. Artificial intelligence can mimic these disruptions to enhance human creativity by introducing novel associations, reframing familiar information, and facilitating unconscious cognitive shifts. Risks include dependency, ethical concerns, and output homogenization due to bias. Integrating psychedelic-inspired cognitive mechanisms into AI design may foster innovative thinking and adaptive problem-solving, provided ethical and practical issues are addressed.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Artificial intelligence: ai Machine learning Computational creativity Creativity enhancement: innovation Creative thinking
Citations 1
Key finding Argues that AI can be designed to mimic psychedelic-induced cognitive disruptions to enhance human creativity, while also addressing associated ethical and practical risks.

Abstract

Psychedelics, such as LSD and psilocybin, disrupt entrenched cognitive patterns by facilitating novel insights and new associations. This paper considers how AI can potentially mimic these psychedelic-induced cognitive disruptions to augment and enhance human creativity. Psychedelics likely enhance creativity by altering brain function, notably the activity of the Default Mode Network, which leads to changes in cognition. Psychologically, they may reduce latent inhibition, increase divergent thinking, and promote implicit learning. Similarly, AI systems can replicate these creative enhancements by introducing novel associations, reframing familiar information, and facilitating unconscious cognitive shifts. The risks associated with AI use are also compared to psychedelics, including dependency, ethical concerns, and homogenization of outputs due to bias. Integrating the cognitive mechanisms activated by psychedelics into AI design provides promising pathways for creativity enhancement. Carefully designed AI could act as a cognitive catalyst, fostering innovative thought processes and adaptive problem-solving while addressing identified ethical and practical concerns.

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