The Effect of Digital Mindfulness Interventions on Depressive, Anxiety, and Stress Symptoms in Pregnant Women: A Systematic Review and Meta-Analysis.
Monique L Mefrouche, Eva-Maria Siegmann, Stephanie Böhme, Matthias Berking, Johannes Kornhuber
European Journal of Investigation in Health, Psychology and Education September 1, 2023 DOI: 10.3390/ejihpe13090122 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and meta-analysis Randomized Peer reviewed |
|---|---|
| Sample size | 1,373 |
| Population | Pregnant women |
| Intervention | digital-based mindfulness interventions |
| Topics | Anxiety Depression Meditation |
| Keywords | Digital Meta-analysis Pregnancy Stress |
| Citations | 15 |
| Key findings | Digital mindfulness interventions significantly reduce depression and anxiety symptoms but not stress symptoms in pregnant women, with effects moderated by attrition rate and primiparity. |
Abstract
Introduction. Pregnancy is a unique time in a woman's life that can be both exciting and challenging. It is also a period that can be associated with significant stress, anxiety, and depression, which can have negative consequences for both the mother and the baby. Mindfulness interventions are known to be a well-suited treatment and prevention method for psychiatric symptoms in pregnancy, and web-based applications have been explored. We here present an up-to-date systematic review and meta-analysis of randomized-controlled trials to investigate the effect of digital-based mindfulness interventions on depressive, anxiety, and stress symptoms during pregnancy. Methods. The systematic literature search and data extraction was performed by two independent raters. It resulted in 13 eligible studies overall comprising 1373 participants. We conducted random-effects meta-analyses for depressive, anxiety, and stress symptoms after completion of a digital mindfulness intervention (compared to a control group). Results. Digital mindfulness intervention methods were significantly able to reduce depression (g = -0.47, 95% CI [-0.9; -0.09]) and anxiety symptoms (g = -0.41, 95% CI [-0.77; -0.05]), but not stress symptoms. These effects were moderated by the attrition rate (βDepression = 0.025, pDepression < 0.01; βAnxiety = 0.022, pAnxiety < 0.01; βStress = 0.022, pStress < 0.01). Primiparity also had a significant influence on the intervention effect regarding depression symptoms (β = 0.033, p = 0.024). Conclusions. Digital mindfulness interventions are a promising method to reduce mental health symptoms in pregnant women. We identified certain parameters moderating this effect, for example, primiparity and the attrition rate.
Comparable studies
Other systematic reviews and meta-analyses on anxiety, most cited first.
Citations in the library
Cited by 11
- Efficacy of online mindfulness for the treatment of insomnia in pregnancy: A randomized clinical trial. PLoS One 2025
- The effectiveness of mHealth mindfulness interventions on perinatal psychological health: a systematic review. Oxford open digital health 2025
- Mindfulness for maternal health: A systematic umbrella review of effectiveness for addressing depression and anxiety symptoms Journal of Affective Disorders Reports October 11, 2026
- Mindfulness-based interventions for perinatal depression, anxiety, and stress: a systematic review and meta-analysis of randomized controlled trials, with an exploratory subgroup signal by delivery mode Frontiers in Psychiatry August 4, 2026
- The Impact of Online Mindfulness Interventions on Postpartum Depression: A Systematic Review and Meta-Analysis. International Journal of Mental Health Nursing August 1, 2025
and 6 more in the library
Cites 9
- Emphasizing mindfulness training in acceptance relieves anxiety and depression during pregnancy. Psychiatry Research April 1, 2022
- Effect of the Mindfulness-Based Stress Reduction program on stress, anxiety, and childbirth fear in pregnant women diagnosed with COVID-19 Complementary Therapies in Clinical Practice February 23, 2022
- Daily Meditation Program for Anxiety in Individuals Admitted to the Antepartum Unit: A Multi-Center Randomized Controlled Trial (MEDITATE). American Journal of Obstetrics & Gynecology MFM 2022
- Effectiveness of Smartphone-Based Mindfulness Training on Maternal Perinatal Depression: Randomized Controlled Trial Journal of Medical Internet Research August 11, 2020
- Mindfulness for pregnancy: A randomised controlled study of online mindfulness during pregnancy. Midwifery October 2018
and 4 more in the library