Epigenetic Repair of Terrifying Lucid Dreams by Enhanced Brain Reward Functional Connectivity and Induction of Dopaminergic Homeostatic Signaling.
Kenneth Blum, Thomas Mclaughlin, Edward J Modestino, David Baron, Abdalla Bowirrat, Raymond Brewer, Bruce Steinberg, A Kenison Roy, Marcello Febo, Rajendra D Badgaiyan, Marks S Gold
Current Psychopharmacology February 15, 2021 DOI: 10.2174/2211556010666210215153513 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 8 |
| Population | Patients with known histories of substance abuse, childhood abuse, and PTSD |
| Intervention | KB200Z |
| Topics | Neuroplasticity Lucid dreaming |
| Keywords | Lucid dreams Dopaminergic homeostatic signaling Functional connectivity Pro-dopamine regulation kb220 |
| Citations | 9 |
| Key findings | Administration of KB200Z eliminated unpleasant or terrifying lucid dreams in 87.5% of eight clinical cases with histories of substance abuse, childhood abuse, and PTSD. |
Abstract
During Lucid Dreams, the dreamer is aware, experiences the dream as if fully awake, and may control the dream content. The dreamer can start, stop, and restart dreaming, depending on the nature and pleasantness of the dream. For patients with Reward Deficiency Syndrome (RDS) behaviors, like Attention Deficit Hyperactivity Disorder (ADHD), Tourette's- Syndrome, and Posttraumatic Stress Disorder (PTSD), the dream content may be pleasant, unpleasant, or terrifying. A sample of psychiatric center patients identified as having RDS reported the effectiveness of a neuronutrient, dopamine agonist, KB200Z, in combating terrifying, lucid dreaming. These reports motivated the study of eight clinical cases with known histories of substance abuse, childhood abuse, and PTSD. The administration of KB200Z, associated with eliminating unpleasant or terrifying lucid dreams in 87.5% of the cases. Subsequently, other published cases have further established the possibility of the long-term elimination of terrifying dreams in PTSD and ADHD patients. Induction of dopamine homeostasis may mitigate the effects of neurogenetic and epigenetic changes in neuroplasticity, identified in the pathogenesis of PTSD and ADHD. The article explores how relief of terrifying lucid dreams may benefit from modulation of dopaminergic signaling activated by the administration of a neuronutrient. Recently, precision formulations of the KB220 neuronutrient guided by Genetic Addiction Risk Score (GARS) test results have been used to repair inheritable deficiencies within the brain reward circuitry. The proposition is that improved dopamine transmodulational signaling may stimulate positive cognitive recall and subsequently attenuate the harmful epigenetic insults from trauma.
Comparable studies
Other case reports and case series on lucid dreaming, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lucid Dreaming as a Learnable Skill: A Case Study The author | 1980 | Case study | n = 1 |
| Lucid Dreaming as a Treatment for Recurrent Nightmares People with recurrent nightmares | 2010 | Case study | n = 5 |
| Lucid dreaming: Correspondence between dreamed and actual events in one subject during rem sleep A lucid dreamer | 1984 | Case study | n = 1 |
| Lucid dreaming treatment for nightmares: A series of cases. Participants with nightmares | 2003 | Case series | n = 8 |
| Nightmares in the Context of PTSD Treated with Psychoeducation Regarding Lucid Dreaming 39-year-old male with a history of suicide attempts and psychiatric admissions | 2010 | Case study | n = 1 |
Citations in the library
Cites 10
- The cognitive neuroscience of lucid dreaming Neuroscience & Biobehavioral Reviews March 14, 2019
- Time for actions in lucid dreams: effects of task modality, length, and complexity Frontiers in Psychology 2014
- Early childhood adversity associations with nightmare severity and sleep spindles. Sleep Medicine April 1, 2019
- KB220Z™ a Pro-Dopamine Regulator Associated with the Protracted, Alleviation of Terrifying Lucid Dreams. Can We Infer Neuroplasticity-induced Changes in the Reward Circuit? Journal of reward deficiency syndrome and addiction science 2016
- Putative dopamine agonist (KB220Z) attenuates lucid nightmares in PTSD patients: role of enhanced brain reward functional connectivity and homeostasis redeeming joy. Journal of Behavioral Addictions June 1, 2015
and 5 more in the library