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Double-Blind Comparison of the Two Hallucinogens Dextromethorphan and Psilocybin: Experience-Dependent and Enduring Psychological Effects in Healthy Volunteers

Samantha Hilbert, David S. Mathai, Nathan D. Sepeda, Justin C Strickland, Roland R. Griffiths, Albert Garcia‐romeu

Psychedelic Medicine August 30, 2023 DOI: 10.1089/psymed.2023.0035 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Analysis Double-blind Peer reviewed
Topics Psilocybin
Keywords Dextromethorphan Hallucinogen Psychotherapist Clinical psychology
Citations 10
Registration NCT02033707
Key points Dissociatives may have clinical utility when explored within supportive contexts characteristic of psychedelic research.

Abstract

This analysis suggests the utility of exploring clinical applications of dissociatives that occur within the supportive contexts that are characteristic of psychedelic research and that prioritize the optimization of psychologically valuable drug experiences. This study was registered with ClinicalTrials.gov (NCT02033707).

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