Mindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial.
Hailiang Zhang, Xiangrong Zhang, Xiaomei Jiang, Runjing Dai, Na Zhao, Weimin Pan, Jiaohong Guo, Jingchun Fan, Shisan Bao
Trials May 2, 2024 DOI: 10.1186/s13063-024-08139-0 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 60 |
| Population | Hypertension patients with depression and/or anxiety |
| Interventions | Mindfulness-based intervention health education for hypertension |
| Duration | 10-week intervention |
| Topics | Anxiety Depression Meditation |
| Keywords | Blood pressure bp Hypertension Mindfulness-based therapy |
| Citations | 19 |
| Key findings | Mindfulness-based intervention reduced depression and anxiety scores by 21.1% and 17.8%, lowered systolic blood pressure by 12.24 mm Hg, and improved self-efficacy and awareness of physical and mental health compared to health education alone. |
Abstract
To evaluate mindfulness-based intervention for hypertension with depression and/or anxiety. 10-week mindfulness-based intervention, including health education for hypertension, exclusively for the control group, was administered to the intervention group to assist sixty hypertension patients with depression/anxiety. Among them, the intervention group comprised 8 men and 22 women, with a mean age of 60.02 years and a mean duration of hypertension of 6.29 years. The control group consisted of 14 men and 16 women with a mean age of 57.68 years and a mean duration of hypertension of 6.32 years. The severity of depressive and/or anxiety symptoms was assessed using the 9-item Patient Health Questionnaire (PHQ-9) and the 7-item Generalized Anxiety Disorder scale (GAD-7), along with blood pressure (BP) measurements taken twice daily. The study utilized a self-made self-efficacy scale and awareness of physical and mental health to evaluate mental health and state. The depression PHQ-9 or GAD-7 scores reduced by 21.1% or 17.8% in the mindfulness-based intervention group, compared to the control (Z = -2.040, P = 0.041) post 10-week period, suggesting significant reduction in anxiety/stress. These results were consistent with a reduction in systolic BP of 12.24 mm Hg (t = 6.041, P = 0.000). The self-efficacy score of the mindfulness intervention group significantly improved compared to the control (t = 7.818, P < 0.001), while the awareness of physical and mental health in the mindfulness intervention group significantly improved compared to the control (χ2 = 5.781, P = 0.016). Mindfulness-based, short-term focused interventions provide modest relief for depression and/or anxiety and are effective in lowering blood pressure and improving self-efficacy scores. Chinese Clinical Trial Registry, ChiCTR1900028258. Registered 16 December 2019, https://www.chictr.org.cn/showproj.html?proj=43627 .
Comparable studies
Other randomized controlled trials on anxiety, most cited first.
Citations in the library
Cited by 5
- Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life Bioengineering August 29, 2025
- The Effects of Mindfulness Techniques on Anxiety, Depression, and Stress, with an Emphasis on Gratitude: A Systematic Review and Meta-Analysis Healthcare February 27, 2026
- Exploring Mechanisms, Methods, and Measurement in Mindfulness Research: A Scoping Review of Community-Based Interventions Mindfulness September 15, 2026
- Impact of mindfulness training on depression and walking ability in patients with lower extremity arteriosclerosis obliterans and depression World Journal of Psychiatry August 19, 2026
- Mindfulness-based interventions to promote improved sleep quality in older adults. Nursing March 1, 2026
Cites 7
- Home practice in Mindfulness-Based Cognitive Therapy and Mindfulness-Based Stress Reduction: A systematic review and meta-analysis of participants' mindfulness practice and its association with outcomes Behaviour Research and Therapy May 10, 2017
- Effects of mindfulness meditation on mindfulness, mental well-being, and perceived stress. Currents in Pharmacy Teaching and Learning August 7, 2019
- Mindfulness-Based Interventions for Anxiety and Depression Psychiatric Clinics of North America September 18, 2017
- Mindfulness-Based Stress Reduction in Advanced Nursing Practice: A Nonpharmacologic Approach to Health Promotion, Chronic Disease Management, and Symptom Control. Journal of Holistic Nursing September 2015
- Mindfulness-based cognitive therapy versus psychoeducational intervention in bipolar outpatients with sub-threshold depressive symptoms: a randomized controlled trial. BMC Psychiatry August 15, 2014
and 2 more in the library