Intensity of Psychoactive Substance Use Affects the Occurrence of Prodromal Symptoms of Psychosis.
Gniewko Więckiewicz, Iga Florczyk, Maciej Stokłosa, Marta Jurga, Piotr Gorczyca, Magdalena Kotlicka-Antczak
Journal of Clinical Medicine January 28, 2024 DOI: 10.3390/jcm13030760 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 703 |
| Population | Users of illegal psychoactive substances recruited via social media |
| Topics | Addiction |
| Keywords | Drug addiction Dudit Pq-b Drugs Prodromal symptoms Psychoactive substance Schizophrenia Mental health Psychosis risk Substance abuse Early intervention |
| Citations | 1 |
| Key findings | Intensity of psychoactive substance use correlated positively with the risk and intensity of prodromal psychosis symptoms. |
Abstract
Psychosis is defined as a series of symptoms that impair the mind and lead to a kind of loss of reference to reality. Development of psychosis is usually preceded by the appearance of prodromal symptoms. Numerous attempts have been made to find out how psychoactive substances can influence the onset and development of psychotic disorders, but to date there are no studies that show a link between the onset of prodromal symptoms and the use of psychoactive substances. A survey consisting of epidemiological and demographic questions, the Drug Use Disorders Identification Test (DUDIT), and the Prodromal Questionnaire Brief Version (PQ-B) was conducted on social media among users of illegal psychoactive substances, covering 703 study participants. A total of 39.8% of the respondents had been treated by a psychiatrist, and the most popular drugs used by respondents in their lifetime were tetrahydrocannabinol-containing products, MDMA, amphetamines, and LSD. A significant correlation was found between the DUDIT and the PQ-B values. Intensity of psychoactive substance use correlated positively with the risk of appearance and intensity of prodromal symptoms of psychosis. Early exposure to psychoactive substances increased the risk of heavy substance use in adulthood and led to more frequent prodromal states.
Comparable studies
Other cross-sectional and survey studies on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey Online survey respondents | 2020 | Cross-sectional survey | |
| The users of Novel Psychoactive Substances: Online survey about their characteristics, attitudes and motivations International users of novel psychoactive substances recruited via bluelight.org | 2016 | Cross-sectional online survey | n = 619 |
| User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study Users of hallucinogenic drugs who completed a web-based questionnaire | 2010 | Cross-sectional survey | n = 600 |
| Psychological and neuropsychological assessment of regular hoasca users. Regular hoasca users from a U.S. branch of União do Vegetal and matched non-user controls | 2016 | Cross-sectional study | n = 57 |
| Client and counselor attitudes toward the use of medications for treatment of opioid dependence. Counselors and clients from outpatient, methadone, and residential drug treatment programs | 2007 | Cross-sectional survey | n = 1,459 |
Citations in the library
Cites 3
- Substance-Induced Psychoses: An Updated Literature Review Frontiers in Psychiatry December 23, 2021
- The Association Between Cannabis Use and Schizophrenia: Causative or Curative? A Systematic Review Cureus July 21, 2020
- Demographic and health characteristics of 3,4-methylenedioxymethamphetamine users (MDMA, ecstasy). Psychiatria Polska October 31, 2022