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Analysis of independent risk factors for postpartum depression in elderly primiparas and the effects of mindfulness-based psychological intervention.

Baihong Wu, Nan Wang, Lili Hu, Guohe Wu

American Journal of Translational Research 2024 DOI: 10.62347/YEMU2258 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Retrospective analysis Peer reviewed
Sample size 75
Population Elderly primiparas with postpartum depression at the First Hospital of Nanchang
Intervention Mindfulness-based psychological intervention
Topics Anxiety Depression Meditation
Keywords Elderly primiparas Mindfulness-based psychological intervention Postpartum depression Self-efficacy
Citations 1
Key points Mindfulness-based psychological intervention improved self-efficacy, emotional well-being, and sleep quality in elderly primiparas with postpartum depression, and advanced maternal age, higher education, pregnancy complications, and lower newborn Apgar score were independent risk factors for postpartum depression.

Abstract

To identify the independent risk factors for postpartum depression in elderly primiparas and to evaluate the effects of mindfulness-based psychological intervention. A retrospective analysis was conducted on 75 women with postpartum depression who received treatment at the First Hospital of Nanchang from January 2021 to March 2022. Among them, 33 women who received routine psychological health management were included in the control group, while the remaining 42 who received mindfulness-based psychological intervention on the basis of routine psychological health management were included in the study group. In addition, 80 women without postpartum depression who delivered during the same period at our hospital were selected as the non-depression group. The self-cognitive function scores, depression and anxiety scores, sleep quality and progesterone level were compared between the two groups before and after the intervention. Logistic regression analysis was used to identify the influencing factors for postpartum depression in elderly primiparas. Before the intervention, no significant difference was found in General Self-Efficacy Scale (GSES) scores between the two groups (P > 0.05). After the intervention, the GSES scores significantly improved in both groups, with the study group showing a significantly higher improvement compared to the control group (P 0.05). After the intervention, the EPDS and GAD-7 scores significantly decreased in both groups, with the study group showing a significantly greater reduction compared to the control group (all P 0.05). After the intervention, the PSQI scores notably decreased in both groups, with the study group showing notably lower scores compared to the control group (P 0.05). After the intervention, progesterone levels significantly decreased in both groups, and the intervention group showed significantly lower levels compared to the control group (P < 0.05). Logistic regression analysis identified age (P < 0.0001; OR: 5.471; 95% CI: 2.504-11.956), education level (P = 0.029; OR: 2.370; 95% CI: 1.094-5.137), pregnancy complications (P = 0.006; OR: 3.665; 95% CI: 1.460-9.199), and newborn Apgar score (P = 0.046; OR: 2.895; 95% CI: 1.017-8.242) as independent risk factors for postpartum depression in elderly primiparas. Mindfulness-based psychological intervention demonstrates positive effects on enhancing self-efficacy, emotional well-being, and sleep quality among elderly primiparas experiencing postpartum depression. Additionally, advanced maternal age, higher education level, presence of pregnancy complications, and relatively lower newborn Apgar score are independent risk factors for postpartum depression in elderly primiparas.

Comparable studies

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Study Year Design Participants
Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Residually depressed patients and nondepressed controls; recovered depressed patients 2002 Observational cohort with intervention components
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression 2017 Observational cohort n = 19
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder 2012 Observational cohort n = 30
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... 2017 Observational cohort n = 59

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