Effect of mindfulness-based intervention in patients with diabetes: a meta-analytic review.
Carlos Said Páez-márquez, Elkin Higuera-Dagovett, Jaime Tomás Rojas-Valencia
Psychology, Health & Medicine April 15, 2025 DOI: 10.1080/13548506.2025.2487948 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and meta-analysis Randomized Peer reviewed |
|---|---|
| Sample size | 987 |
| Population | Patients diagnosed with diabetes |
| Intervention | mindfulness-based interventions |
| Duration | 12–20 weeks follow-up |
| Topics | Meditation |
| Keywords | Diabetes mellitus Diabetes complications Mindfulness-based stress reduction |
| Citations | 1 |
| Key findings | Mindfulness-based interventions reduced HbA1c by 0.5 percentage points and lowered depression scores at 12–20 weeks follow-up. |
Abstract
Traditional management strategies for diabetes primarily focus on behavioural risk factors and pharmacological therapies. Furthermore, mindfulness-based interventions (MBIs) aim to assist patients in recognising and accepting sensations, emotions and cognitions without automatic reactivity. This approach can potentially enhance glycaemic control and mental health in diabetic patients. This systematic review and meta-analysis aim to assess the effects of MBIs among individuals diagnosed with diabetes. A systematic literature search and meta-analysis were conducted following international quality standards utilised by the Cochrane Collaboration. Randomised controlled trials were included. The population of interest was defined as any patient diagnosed with diabetes; MBIs were defined as the intervention. Pubmed, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials and Lilacs were accessed. A grey literature search was performed using OpenGrey and ClinicalTrials tools. Outcomes included changes in glycosylated haemoglobin percentage (%HbA1c), depression, and stress scores. The risk of bias was assessed using the RoB 2 tool, and publication bias was evaluated through Egger's test. The results were presented with forest plots. The mean difference (MD) for the %HbA1c and the standardised MD for the measurement scale scores were used as effect measures. The initial search retrieved 442 scientific articles, 11 randomised clinical trials were finally selected for the systematic review, which included 987 participants (487 in the intervention groups), and seven articles were included in the meta-analysis. The meta-analysis showed that MBIs had effects at follow-up (between 12 and 20 weeks) in reducing %HbA1c levels (MD = -0.5, CI 95% [-0.67, -0.34]) and depression SMD = -0.84, CI 95% [-1.11, -0.56]). It is proposed that mindfulness significantly enhances mental health and glycaemic control in patients with diabetes. Further research is warranted to confirm these effects and gain a deeper understanding of the contribution of MBIs in comprehensive diabetes treatment.
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cites 12
- Intervenciones psicológicas basadas en mindfulness y sus beneficios: estado actual de la cuestión Clínica y Salud October 10, 2016
- Mindfulness-Based Interventions and the Hypothalamic-Pituitary-Adrenal Axis: A Systematic Review. Neurology International November 20, 2024
- The effectiveness of mindfulness-based stress reduction (MBSR) on the mental health, HbA1C, and mindfulness of diabetes patients: A systematic review and meta-analysis of randomised controlled trials. Applied Psychology: Health and Well-Being February 28, 2023
- Evaluation of the effects of 12 weeks mindfulness-based stress reduction on glycemic control and mental health indices in women with diabetes mellitus type 2 Advanced Biomedical Research November 4, 2020
- Mindfulness and Behavior Change Harvard Review of Psychiatry November 1, 2020
and 7 more in the library