Chain mediation of rumination and anxiety state between mindfulness and depressed mood in infertile women.
Shiqi Luo, Biru Luo, Zihang Wei, Xin Liao
Scientific Reports April 23, 2025 DOI: 10.1038/s41598-025-99147-w (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional study Peer reviewed |
|---|---|
| Sample size | 946 |
| Population | Women with infertility from a maternal and child hospital in western China |
| Topics | Anxiety Depression Meditation |
| Keywords | Infertility Rumination thinking |
| Citations | 2 |
| Key findings | Mindfulness influences depressed mood in infertile women both directly and indirectly through the chain-mediated effects of rumination thinking and anxiety state. |
Abstract
The study aims to explore the relationship between mindfulness, rumination thinking, anxiety state, and depressed mood, and the chain mediating roles of rumination thinking and anxiety state in explaining how mindfulness influences depressed mood in infertile women. This cross-sectional study included 946 women with infertility from a maternal and child hospital in western China through convenience sampling. Five Facet Mindfulness Questionnaire (FFMQ), Rumination Response Scale (RRS), Self-rating Anxiety Scale (SAS), and Self-rating Depression Scale (SDS) were measured as outcome indicators. SPSS PROCESS macro program was used to test for chained mediating effects and the significance using the Bootstrap method. The total effect of mindfulness on depressed mood was -0.390 with the direct path effect of -0.170. The total indirect path effect was -0.220, which accounted for 56.4% of the total effect, and that the chain mediated path (FFMQ→RRS→SAS→SDS) effect was significant with a mediation effect value of -0.075. Mindfulness can not only directly affect infertile women's depressed mood, but also indirectly affect that through the chain-mediated effects of rumination thinking and anxiety state.
Comparable studies
Other cross-sectional and survey studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic | 2020 | Cross-sectional survey | n = 985 |
| The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms Internet survey respondents reporting challenging experiences with psilocybin | 2016 | Questionnaire development and validation | |
| Psychedelics and Mental Health: A Population Study Adult population in the United States | 2013 | Cross-sectional survey | n = 130,152 |
| Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users Ecstasy users who participated in a WWW study of recreational drug use | 2002 | Cross-sectional survey | n = 282 |
| 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures | 2019 | Cross-sectional survey | n = 362 |
Citations in the library
Cites 12
- Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis The Journal of Alternative and Complementary Medicine May 1, 2009
- Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Journal of Child Psychology and Psychiatry October 22, 2018
- The effects of mindfulness therapy on infertile female patients: A meta-analysis. Technology and health care : official journal of the European Society for Engineering and Medicine 2024
- Mindfulness on Rumination in Patients with Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. International Journal of Environmental Research and Public Health December 1, 2022
- The Comparative Efficacy of Unified Transdiagnostic Protocol (UP) and Mindfulness-Based Stress Reduction Protocol (MBSR) on Emotion Regulation and Uncertainty Intolerance in Infertile Women Receiving IVF. Journal of clinical psychology in medical settings October 30, 2022
and 7 more in the library