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Exploring the Effects of Mindfulness on Adolescent Depression-Findings from a Longitudinal Study.

Filipa Ćavar, Josipa Mihić, Goran Milas

Healthcare April 15, 2025 DOI: 10.3390/healthcare13080906 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Longitudinal study Peer reviewed
Sample size 1,618
Population Secondary school students aged 16-17
Duration Three-wave longitudinal study
Topics Depression Meditation
Keywords Adolescents Mental health
Citations 3
Key findings Higher trait mindfulness and even temporary increases in mindfulness are associated with fewer depressive symptoms in adolescents.

Abstract

Background/Objectives: Adolescence is a critical period for mental health, with depression increasing rapidly and often leading to lifelong consequences. In recent decades, the prevalence of elevated depressive symptoms among adolescents has steadily risen, making it a significant public health concern. While research supports the benefits of mindfulness-based practices in reducing adolescent depressive symptoms, the role of trait mindfulness remains underexplored. Although some studies suggest a link between trait mindfulness and lower depressive symptomatology, a longitudinal perspective could provide deeper insights into this relationship. Given adolescents' heightened vulnerability to mental health issues, understanding the potential causal link between trait mindfulness and depression is crucial for both prevention and intervention efforts.

Methods: This study examines the relationship between mindfulness and depression in a three-wave longitudinal study of 1618 secondary school students (Males: N = 671, M = 16.4 years, SD = 0.60; Females: N = 947, M = 16.3 years, SD = 0.65) using a random intercept cross-lagged panel model.

Results: Findings indicate that mindfulness and depression share a substantial proportion of variance (r = 0.48) at the stable trait level, suggesting that sustained attentional focus, a hallmark of mindfulness, is consistently associated with fewer depressive symptoms. At the within-person level, momentary deviations from stable mindfulness levels in the first and second waves were linked to lower depressive symptoms in subsequent waves (β = -0.21, p = 0.016; β = -0.44, p = 0.03, respectively). These findings suggest that even temporary increases in mindfulness may provide additional protection against depression.

Conclusions: Overall, the results suggest that trait mindfulness is associated with a reduced risk of developing depressive symptoms at both the between-person and within-person levels. Specifically, adolescents with higher stable levels of mindfulness tend to report fewer depressive symptoms over time, and even momentary increases in mindfulness beyond an individual's typical level are linked to reductions in subsequent depressive symptoms. These findings highlight the potential of mindfulness-based interventions in mitigating adolescent depression and underscore the importance of cultivating mindfulness as a protective factor during this critical stage of development.

Comparable studies

Other observational and cohort studies on depression, most cited first.

Study Year Design Participants
Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Residually depressed patients and nondepressed controls; recovered depressed patients 2002 Observational cohort with intervention components
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression 2017 Observational cohort n = 19
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder 2012 Observational cohort n = 30
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... 2017 Observational cohort n = 59

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