Extraction studies of Tabernanthe iboga and Voacanga africana.
Natural product letters February 1, 2002 DOI: 10.1080/1057563029001/4881 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Method development and optimization Peer reviewed |
|---|---|
| Topics | Ibogaine |
| Keywords | Plant extraction Botanical extraction Compound isolation Alkaloid extraction Natural product extraction Phytochemical extraction Isolation technique Natural compound extraction Cost-effective methods Affordable techniques Low-cost processes Economical methods Inexpensive solutions Budget-friendly extraction Simplified process Iboga alkaloid Addiction treatment compound *tabernanthe iboga* compound Psychoactive alkaloid Novel extraction technique Innovative process Breakthrough method Simple extraction Chemical process Research innovation New method Extraction technology |
| Citations | 48 |
| Key points | A simplified extraction using only diluted vinegar and ammonia successfully isolates ibogaine and related alkaloids from T. iboga and V. africana bark. |
Abstract
The root bark of Tabernanthe iboga contains ibogaine as its predominant alkaloid and has been an important source of it. Ibogaine is used experimentally to interrupt drug addiction and allow therapeutic intervention, but is currently unaffordable to doctors in less economically developed countries. To meet this need, an extraction of alkaloids from T. iboga root bark was optimized and simplified to use only diluted vinegar and ammonia, and was successfully applied to related alkaloids from Voacanga africana bark also. The alkaloids were converted to their hydrochlorides and purified, and the minor alkaloids were recovered.
Citations in the library
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- A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature 2021
- The ibogaine medical subculture. Journal of Ethnopharmacology January 4, 2008
- The Anti-Addiction Drug Ibogaine and the Heart: A Delicate Relation Molecules January 29, 2015
- Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review. Human & Experimental Toxicology March 1, 2008
- Fatalities temporally associated with the ingestion of ibogaine. Journal of Forensic Sciences March 1, 2012
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