Recent advances in the neuropsychopharmacology of serotonergic hallucinogens.
Behav Brain Res July 15, 2014
Recent advances in the neuropsychopharmacology of serotonergic hallucinogens are reviewed, highlighting how these compounds act primarily through serotonin 2A receptors to produce their characteristic subjective effects and potential therapeutic benefits. The review discusses findings from human and animal studies on the neural mechanisms underlying altered states of consciousness, including changes in brain network connectivity and neuroplasticity. It also examines the clinical implications for treating conditions such as depression, anxiety, and addiction, while noting the need for further research to fully understand the therapeutic potential and risks.