Wiley Interdisciplinary Reviews Forensic Science

The use of prodrugs as drugs of abuse

Wiley Interdisciplinary Reviews Forensic Science March 19, 2024 Julio Ponce 6 citations

Abstract Prodrugs are an important strategy for the development and design of therapeutic drugs. They involve the addition of an easily removable group (such as an ester) to a molecule in order to chemically protect it from metabolism, hydrolysis, or interaction with tissues. In the therapeutic drug market, prodrugs may reduce adverse effects, lead to more accurate tissue delivery, increase...