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Iranian Journal of Psychiatry

ISSN 1735-4587

2 papers in the library · publishing 2015-2022

Papers

Ketamine and Other Glutamate Receptor Modulating Agents for Treatment-Resistant Depression: A Systematic Review of Randomized Controlled Trials.

Iranian Journal of Psychiatry July 1, 2022 Ahmad Shamabadi, Ali Ahmadzade, Ali Aqamolaei et al.

A systematic review of 38 randomized controlled trials found compelling evidence that ketamine (with or without electroconvulsive therapy, intravenous or other forms), nitrous oxide, amantadine, and rislenemdaz (MK-0657) are effective for treatment-resistant depression, though results for the latter three were each based on a single study. Lithium, lanicemine, D-cycloserine, and decoglurant showed mixed results, while riluzole and 7-chlorokynurenic acid were mostly comparable to placebo. High heterogeneity among trials prevented determining the difference between statistical and clinical significance. Ketamine appears efficacious, but optimal dosage, duration, and intervals remain unclear.

DOI: 10.18502/ijps.v17i3.9733 (opens in new tab) Full text (opens in new tab) Depressive disorder Behavioral symptoms Glutamate receptor Glutamates +3

Zār Spirit Possession in Iran and African Countries: Group Distress, Culture-Bound Syndrome or Cultural Concept of Distress?

Iranian Journal of Psychiatry September 1, 2015 Fahimeh Mianji, Yousef Semnani

Zār is a form of spirit possession found in northern and eastern Africa and parts of the Middle East. Its prevalence, clinical features, and social context differ across regions, despite shared cultural roots from a history of slavery. This review examines how zār is classified in DSM-IV and DSM-V, and how it manifests in Iran, Sudan, Ethiopia, and Egypt. The paper aims to help mental health clinicians understand zār as a cultural concept, especially for Iranian, Middle Eastern, and African immigrants living near the Persian Gulf coast.

Medicine History Psychology Sociology