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Fitoterapia

ISSN 1873-6971

5 papers in the library · 29 citations · publishing 2010-2023

Papers

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Natural psychedelics in the treatment of depression; a review focusing on neurotransmitters.

Fitoterapia September 1, 2023 Samane Jahanabadi, Shayan Amiri, Mehdi Karkeh-Abadi et al. 14 citations

Natural psychedelic compounds are emerging as potential novel therapeutics in psychiatry. This review will discuss how natural psychedelics exert their neurobiological therapeutic effects, and how different neurotransmission systems mediate the effects of these compounds. Further, current therapeutic strategies for depression, and novel mechanism of action of natural psychedelics in the...

DOI: 10.1016/j.fitote.2023.105620 (opens in new tab) Full text (opens in new tab) Depression Dimethyltryptamine Psilocybin Natural psychedelics +5

Central nervous system activity of a Tabernaemontana arborea alkaloid extract involves serotonergic and opioidergic neurotransmission in murine models.

Fitoterapia September 1, 2023 M E González-trujano, N Páez-martínez, Felix Krengel et al. 4 citations

Tabernaemontana arborea (Apocynaceae) is a Mexican tree species known to contain ibogan type alkaloids. This study aimed at determining central nervous system-related activities of an alkaloid extract obtained from the root bark of T. arborea. A gas chromatography-mass spectrometry (GC-MS) analysis was performed to describe the alkaloid profile of the extract. A wide dosing range (0.1 to 56.2...

DOI: 10.1016/j.fitote.2023.105602 (opens in new tab) Full text (opens in new tab) Antidepressant-like activity Antinociceptive Memory impairment Tabernaemontana phytochemistry: tabernaemontana +13

Heteroaromatic salvinorin A analogue (P-3 l) elicits antinociceptive and anxiolytic-like effects.

Fitoterapia June 1, 2023 Caroline V. L. Moreira, Ana Luiza G Faria, Daiany P B Silva et al. 2 citations

Previous studies have attributed the prominent analgesic, hallucinogenic, sedative, and anxiolytic properties of Salvia divinorum to Salvinorin A. However, the overall pharmacological profile of this isolate limits its clinical applications. To address these limitations, our study evaluates the C(22)-fused-heteroaromatic analogue of salvinorin A [2-O-salvinorin B benzofuran-2-carboxylate]...

DOI: 10.1016/j.fitote.2023.105488 (opens in new tab) Full text (opens in new tab) Antinociceptive Anxiolytic Benzodiazepine site Opioid receptors +14

Desmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor.

Fitoterapia October 2014 Kang-Kang Zhi, Zhong-Duo Yang, Dan-Feng Shi et al.

Desmodeleganine (1), a new potential monoamine oxidase inhibitor, along with three known alkaloids, bufotenin (2), hydroxy-N, N-dimethyltryptamine N(12)-oxide (3), 2-(5-methoxy-1H-indol-3-yl)-N, and N-dimethylethylamine (4) were isolated from the leaves of Desmodium elegans. Their structures were elucidated by IR, MS, 1D and 2D NMR spectra. 1 showed strong monoamine oxidase inhibitory activity...

DOI: 10.1016/j.fitote.2014.07.022 (opens in new tab) Full text (opens in new tab) Alkaloids Desmodium elegans Monoamine oxidase inhibitors

A new indole alkaloid from Ervatamia yunnanensis.

Fitoterapia 2010 Yong-Sheng Jin, Jing-Ling Du, Hai-Sheng Chen et al. 9 citations

The stems of Ervatamia yunnanensis have afforded a new indole alkaloid, ervataine (1), whose structure was determined by spectroscopic analysis. Five known compounds, ibogaine (2) coronaridine (3), heyneanine (4), voacangine hydroxyindolenine (5) and coronaridine hydroxyindolenine (6), were also isolated.

DOI: 10.1016/j.fitote.2009.07.008 (opens in new tab) Full text (opens in new tab) Phytochemistry Indole alkaloids Ervatamia yunnanensis Natural products