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JME Practical Bioethics

ISSN 3049-8600

3 papers in the library · publishing 2026

Papers

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Parallel-access compounds: unregulated availability as a consideration in research ethics

JME Practical Bioethics July 1, 2026 Edward Jacobs, Edward Palmer, Celia J. A. Morgan

Some investigational compounds exist in both regulated clinical pipelines and unregulated street or online markets. Ketamine, psychedelics and cannabis are all under active clinical investigation while remaining accessible, in unregulated form, through illicit channels without clinician oversight. We propose the term parallel-access compounds for this category and argue that it deserves...

If you respect someone, let them go? Personal autonomy and physical safety in psychedelic treatments

JME Practical Bioethics July 1, 2026 Christopher Poppe, Chiara Caporuscio, Dimitris Repantis

Psychedelic treatments hold significant therapeutic promise for various psychiatric conditions. However, their unique therapeutic setting with psychedelic substance dosing sessions presents a particular ethical issue concerning patient autonomy. This article explores the ethics of limiting personal autonomy and freedom of movement during dosing sessions due to concerns for physical safety....

Market approval and the right to health: a human rights perspective on MDMA-assisted therapy

JME Practical Bioethics April 1, 2026 Christoph Bublitz

The application for MDMA-assisted therapy (MDMA-AT) and its rejection by the FDA in 2024 prompted a debate about ethical aspects in drug regulation. This paper examines central issues raised in that debate through the lens of human rights, especially the right to health. It argues that drug approval decisions must take into account the multipolar constellation of and dependencies between...