Effects and mechanisms of esketamine on depression by targeting gut microbiota: A narrative review
New Discovery April 30, 2025 Jia-Qi Liu, Chen Zhou
Depression is a severe and recurrent neuropsychiatric disease with high prevalence, disability, and mortality, which imposes a heavy burden on national public health and the economy. Traditional antidepressants demonstrate delayed effects, low cure rates, and inadequate therapeutic effectiveness for managing treatment-resistant depression. Numerous studies have proved that esketamine, a...