Exploration of Neuroprotective Therapy

Diverse avenues of research support the transmethylation theory of psychosis: implications for neuroprotection

Exploration of Neuroprotective Therapy May 21, 2024 Christine L. Miller

Transmethylation in the context of psychiatry has historically referred to the enzymatic transfer of a methyl group from one biochemical to another, whose resulting function can change so dramatically that a biochemical like tryptamine, for example, is converted into the hallucinogen dimethyltryptamine. Central to endogenous methylation activity is the folate cycle, which generates the primary...