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Physiology

ISSN 1548-9213

2 papers in the library · 1 citation · publishing 2024

Papers

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Pain Relief: Unique Derivatives of Ibogaine Alleviate Both Acute and Chronic Pain Symptoms

Physiology May 1, 2024 Sanjit Dey, Tuhin Bhattacharya, Surajit Sinha 1 citation

Pain induction results in the initiation of neuroinflammatory and neurodegenerative processes, leading to neuromodulation, while conventional analgesic treatments frequently entail undesirable side effects. This research delves into the potent and selective analgesic attributes of Iboga derivatives in the context of acute and chronic pain models. Specifically, the study explores the effcacy of...

Effect of Intravenous Delivery of N,N Dimethyltryptamine on Sleep-Wake States in Rat

Physiology May 1, 2024 Rachel Summerfield, Trent Groenhout, Tiecheng Liu et al.

Psychedelics, including N, N, Dimethyltryptamine (DMT), are being increasingly explored for therapeutic potential to treat psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder. These and other psychiatric conditions have a bidirectional relationship with sleep patterns but the impact of psychedelics, particularly DMT, on sleep architecture is incompletely...