Journal of Medicine Surgery and Public Health

Reconsidering Ibogaine for the treatment of severe mental illness and substance use disorders

Journal of Medicine Surgery and Public Health August 25, 2025 R. Andrew Yockey 2 citations

Severe mental illness (SMI) and co-occurring substance use disorders (SUDs) continue to pose a major global health challenge, contributing to high rates of mortality, disability, and economic strain. Ibogaine, a naturally occurring psychoactive compound derived from the Tabernanthe iboga plant, has shown promise in easing withdrawal symptoms, reducing cravings, and improving psychiatric...