Critical CareJanuary 23, 2026Abdulrahman Ibrahim Alzmmam, Reema Fahad Alghanem, Asma Alshahrani et al.
Optimal pain and sedation management in intensive care unit (ICU) remains challenging. While opioids and benzodiazepines are widely used, their adverse effects highlight the need for alternative or adjunctive strategies. Ketamine, with its analgesic and opioid-sparing has been proposed as an adjuvant. However, current evidence regarding its efficacy in ICU patients, particularly within the...
Background So far, the few prospective studies on near-death experience (NDE) were carried out only in intensive care unit (ICU) patients with homogeneous aetiologies, such as cardiac arrest or trauma survivors. The aims of this 1-year prospective and monocentric study were to investigate the incidence of NDE in ICU survivors (all aetiologies) as well as factors that may affect its frequency,...
INTRODUCTION: Near-death experiences (NDEs) are reported by 11-23% of cardiac arrest survivors. Several theories concerning the mechanisms of NDEs exist - including physical, psychological, and transcendental reasons - but so far none of these has satisfactorily explained this phenomenon. In this study, we investigated the effect of partial pressures of O2 and CO2, and serum levels of Na and K...
Klemenc-Ketis and colleagues’ novel report of hyper capnia and hypokalemia associated with near-death experiences (NDEs) [1] was somewhat surprising, as Sabom [2] had previously reported lower than normal carbon dioxide levels measured at the time of a patient’s NDE, and Parnia and colleagues, in a prospective study of 63 cardiac arrest survivors, had found no signifi cant association of either...