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QJM

ISSN 1460-2393

2 papers in the library · 214 citations · publishing 1998-2002

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Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions

QJM July 1, 1998 Ian G. Mills 92 citations

We have previously shown that eating disorders are a compulsive behaviour disease, characterized by frequent recall of anorexic thoughts. Evidence suggests that memory is a neocortical neuronal network, excitation of which involves the hippocampus, with recall occurring by re-excitement of the same specific network. Excitement of the hippocampus by glutamate-NMDA receptors, leading to long-term...