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Physiology International

ISSN 2498-602X

1 paper in the library · publishing 2025

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Treatment-resistant major depression: Systematic review of comparative efficacy of electroconvulsive therapy and ketamine

Physiology International January 30, 2025 Giullia Graeff Saldanha, Leonardo Locatelli, Izidione Antônio Miozzo Junior

AbstractDepression is the leading cause of disability worldwide. Major Depressive Disorder (MDD) is a condition characterized mostly by low or depressed mood as well as difficulty experiencing emotions, whether positive or negative. Poor adherence has sparked the interest from both physicians and patients in these alternative therapeutic approaches. Ketamine and Electroconvulsive Therapy (ECT)...