Imaging neuroscience (Cambridge, Mass.)
2026
Hongkeun Kim
Why do some moments imprint themselves in memory while others vanish without a trace? This meta-analysis identifies a dissociation in large-scale brain networks during encoding: networks associated with impairing encoding are task-invariant, whereas those supporting it are task-specific. Drawing on 56 functional magnetic resonance imaging (fMRI) studies employing the subsequent memory paradigm,...
Imaging neuroscience (Cambridge, Mass.)
2026
Fan Nils Yang, Dante Picchioni, Jacco A De Zwart et al.
Functional connectomes (FCs) derived from fMRI are unique to an individual and can be reliably distinguished from those of others. However, the neurobiological basis for this "fingerprint"-like uniqueness remains unclear. One hypothesis holds that FC fingerprinting reflects idiosyncratic conscious experiences, while an alternative suggests that stable, intrinsic brain functional network...
Imaging neuroscience (Cambridge, Mass.)
2026
Tiara Bounyarith, David Braun, Aaron Kucyi
Much of a typical individual's mental life is characterized by spontaneous thoughts that occur independently of external stimuli. In prior studies, ongoing mental experiences and their neural correlates have been captured using thought probes presented at random intervals during functional magnetic resonance imaging (fMRI). However, this approach results in temporally imprecise estimates of...
Imaging neuroscience (Cambridge, Mass.)
2026
Ankan Biswas, Srishty Aggarwal, Kanishka Sharma et al.
Visual stimuli-induced "narrowband" gamma oscillations (30-70 Hz) are generated due to excitation-inhibition interactions and are linked to attention/binding. These oscillations attenuate with aging and neurodegeneration, potentially indicating declining inhibitory function. In contrast, meditation enhances endogenous stimulus-free gamma (power in a broad frequency range above 25 Hz). However,...
Imaging neuroscience (Cambridge, Mass.)
2025
Sebastian Ehmann, Idil Sezer, Isaac N Treves et al.
9 citations
Mindfulness meditation is a systematic training in equanimity, sensory clarity, and concentration rooted in ancient contemplative traditions. Here, we synthesized cognitive-behavioral outcomes in long-term meditators (LTMs) resulting from diverse, prolonged meditation practices. Preliminary evidence suggests that LTMs exhibit increased cognitive-sensory integration and decoupling of affective...
Imaging neuroscience (Cambridge, Mass.)
2025
Brandon Taraku, Jason S Nomi, Artemis Zavaliangos-Petropulu et al.
Ketamine produces fast-acting antidepressant effects in treatment-resistant depression (TRD). Prior studies have shown altered functional dynamics between brain networks in major depression. We thus sought to determine whether functional brain network dynamics are modulated by ketamine therapy in TRD. Participants with TRD (n = 58, mean age = 40.7 years, female = 48.3%) completed resting-state...
Imaging neuroscience (Cambridge, Mass.)
2025
Ruiqi Chen, Matthew Singh, Todd S. Braver et al.
Analyses of functional connectivity (FC) in resting-state brain networks (RSNs) have generated many insights into cognition. However, the mechanistic underpinnings of FC and RSNs are still not well-understood. It remains debated whether resting-state activity is best characterized as reflecting noise-driven fluctuations around a single stable state, or instead, as a nonlinear dynamical system...
Imaging neuroscience (Cambridge, Mass.)
2024
Hanna Molla, Giovanni Novembre, Anya K. Bershad et al.
The stimulant ± 3,4-methylenedioxymethamphetamine (MDMA) has been shown to enhance the perceived pleasantness of touch. However, the underlying neural processes contributing to touch-related effects of MDMA are not well understood. Using a double-blind, randomized, within-subject design, this study used fMRI to examine hemodynamic changes following MDMA (1.5 mg/kg) vs. lactose placebo...
Imaging neuroscience (Cambridge, Mass.)
2023
Ioanna Amaya, Marianna E. Schmidt, Marie T Bartossek et al.
The thalamus is primarily known as a relay for sensory information; however, it also critically contributes to higher-order cortical processing and coordination. Thalamocortical hyperconnectivity is associated with hallucinatory phenomena that occur in various psychopathologies (e.g., psychosis, migraine aura) and altered states of consciousness (ASC; e.g., induced by psychedelic drugs)....