Indolealkylamines: Biotransformations and Potential Drug–Drug Interactions
The AAPS Journal May 3, 2008 Ai-Ming Yu 60 citations
Indolealkylamine (IAA) drugs are 5-hydroxytryptamine (5-HT or serotonin) analogs that mainly act on the serotonin system. Some IAAs are clinically utilized for antimigraine therapy, whereas other substances are notable as drugs of abuse. In the clinical evaluation of antimigraine triptan drugs, studies on their biotransformations and pharmacokinetics would facilitate the understanding and...