Psilocybin or Nicotine Patch for Smoking Cessation: A Pilot Randomized Clinical Trial
Mendeley Data February 2, 2026 Matthew Johnson
BACKGROUND. Annual tobacco-related deaths are estimated at 480,000 in the US and 8 million worldwide, dwarfing mortality for all other drugs of abuse. Most smoking cessation interventions result in modest long-term success rates. A pilot study in 15 treatment-resistant smokers found psilocybin with cognitive behavioral therapy resulted in 80% point-prevalence abstinence rates at 6 months....