Among 48 ovarian cancer patients undergoing chemotherapy, a four-week mindfulness training program delivered through virtual reality significantly reduced anxiety, depression, and cancer-related fatigue. Patients reported high acceptance of the virtual reality-based training, which included personalized curriculum, intelligent monitoring, emotion tracking, and games. Scores on the Hospital Anxiety and Depression Scale and Cancer-Related Fatigue Scale improved after the intervention, with the differences being statistically significant. The findings suggest that integrating virtual reality with mindfulness training can help alleviate psychological distress and fatigue during chemotherapy for ovarian cancer.
A meta-analysis of 14 randomized controlled trials involving 1784 patients found that mindfulness-based interventions, compared with conventional care, effectively relieve anxiety, depression, and perceived stress in women with infertility, and improve quality of life, including physiological function, role limitations due to physical problems, vitality, and mental health. The evidence suggests mindfulness therapy can reduce stress and enhance well-being, but the authors note that the quantity and quality of the literature are limited, calling for more multi-center, large-sample, high-quality randomized controlled trials.