ANPAbstract_CBN26October 7, 2026Otávio Durigon Cocco, Marina Rodrigues da Silva, Gabriel Fernandes Gonçalves et al.
Background: The hippocampus is a key structure for memory and neuronal integration, comprising subregions with distinct morphological and functional properties. Among them, CA1 and CA3 display specific organizational features: CA1 is highly plastic and commonly used as a marker of morphophysiological changes associated with cognition, whereas CA3 is characterized by recurrent circuits and high...
ANPAbstract_CBN26October 7, 2026S. Graça, I. B. Bustelli, Erica Vitoria Santos et al.
Background: Alzheimer's disease (AD) is characterized by the deposition of β-amyloid protein (βA), forming amyloid plaques that increase neuroinflammation, mainly in the hippocampus (HPC). One of the substances obtained from the Ayahuasca tea, Banisteriopsis caapi (B.caapi), has an inhibitory effect on monoamine oxidase. Objective: The present work investigated the chronic effects of B.caapi in...
Background: Major depressive disorder is a leading cause of disability worldwide, affecting nearly 300 million people. A substantial proportion of patients develop treatment-resistant depression (TRD), characterized by inadequate response to at least two antidepressant therapies. Ketamine has emerged as a promising therapeutic option due to its rapid antidepressant effects mediated through...