3,4‐Methylenedioxymethamphetamine (ecstasy)‐induced hepatotoxicity: effect on cytosolic calcium signals in isolated hepatocytes
Liver June 1, 1999 G. Beitia, A. Cobreros, L. Sainz et al.
Abstract:Aims/Background: Hepatocellular damage has been reported as a consequence of 3,4‐methylenedioxymethamphetamine (MDMA) intake. However, little is known about the cellular mechanisms involved. The present study was undertaken to evaluate the effects of MDMA on cell viability as well as free calcium levels ([Ca2+]i) in short‐term cultured hepatocytes. Reduced glutathione (GSH),...