Neuromuscular Disorders

Predictors of functional disability in nitrous oxide induced myeloneuropathy: an observational study.

Neuromuscular Disorders May 1, 2026 Ignacio Lopera-Rodríguez, Alicia Silva-Cátedra, Alexandra Rincón-Valencia et al.

Recreational nitrous oxide (N₂O) use is an emerging cause of severe neurotoxicity due to vitamin B12 inactivation. This study analyzes the relationship between initial clinical, biochemical and neuroimaging findings and functional disability at discharge in a cohort of 10 patients recruited between 2024 and 2025. All patients presented with hyperhomocysteinemia, while only 40% showed vitamin...