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Drugs in Context

ISSN 1740-4398

1 paper in the library · publishing 2026

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A review of dextromethorphan and bupropion (Auvelity™) for the treatment of agitation in Alzheimer’s disease

Drugs in Context October 7, 2026 Rajesh R. Tampi, Kayla Murphy, Julia C. Golden et al.

Dextromethorphan hydrobromide and bupropion hydrochloride extended-release tablets (AuvelityTM) became the second medication to be approved by the FDA for the treatment of agitation in Alzheimer’s disease dementia after brexpiprazole. It also became the first non-antipsychotic medication to be approved for this specific indication. In this Editorial, the available data regarding the efficacy...