Durability of antidepressant effects following ketamine based interventions in adults with treatment-resistant depression: A systematic review of randomized controlled trials
International Journal of Pharmaceutical and Clinical Research October 1, 2026 H Gayathri, J Nivedhya, K Purushothama Reddy et al.
Aim: To assess the effectiveness of ketamine-based treatment for adults with treatment-resistant depression in terms of the persistence of antidepressant responses or remission after treatment discontinuation. Data Sources: PubMed/MEDLINE database search was performed to select randomized clinical trials that assessed the effect of ketamine interventions on TRD in adults. Study Selection: The...