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Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

ISSN 0277-0008

1 paper in the library · 5 citations · publishing 2010

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Acute Psychosis Associated with Dissociated Sleep‐Wakefulness State After Mirtazapine Treatment

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy March 24, 2010 Alan R. Felthous, Philip J. Wenger, Rod Hoevet 5 citations

Tricyclic antidepressants decrease rapid eye movement (REM) sleep and may suppress sleep atonia. Reports indicate that these agents can induce visual hallucinations, sometimes characterized as hypnopompic or associated with a dissociated sleep-wakefulness state. In addition, disturbing dreams and confusional states were reported during clinical trials and in subsequent studies. To our...