Dynamic reconfiguration of directed effective connectivity between attention networks and the default mode network in knee osteoarthritis: a combined resting-state and non-noxious thermal stimulation functional magnetic resonance imaging study
The Korean journal of pain October 1, 2026 Weiming Luo, Jun Zhou, Shirui Cheng et al.
Background: Chronic pain is understood as a disturbance of large-scale brain-network organization involving systems that coordinate internally and externally oriented processing. In knee osteoarthritis (KOA), altered connectivity involving attention networks and the default mode network (DMN) has been reported, but directed organization and reconfiguration during non-noxious somatosensory input...