Acute Ketamine Infusion in Rat Does Not Affect In Vivo [11C]ABP688 Binding to Metabotropic Glutamate Receptor Subtype 5.
Molecular imaging 2018 Lauren Kosten, Jeroen Verhaeghe, Leonie Wyffels et al.
Detecting changes in metabotropic glutamate receptor 5 (mGluR5) availability through molecular imaging with the positron emission tomography (PET) tracer [11C]ABP688 is valuable for studying dysfunctional glutamate transmission associated with neuropsychiatric disorders. Using an infusion protocol in rats, we visualized the acute effect of subanesthetic doses of ketamine on mGluR5 in rat brain....
DOI: 10.1177/1536012118788636 (opens in new tab)
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Ketamine
Glutamate
Mglur5
Molecular imaging