Journal of biomolecular structure & dynamics

Intermolecular interactions between DNA and methamphetamine, amphetamine, ecstasy and their major metabolites.

Journal of biomolecular structure & dynamics September 2018 Arthur F V F Reis, Igor L P Gonçalves, Abel F G Neto et al.

In this work, we carried out a theoretical investigation regarding amphetamine-type stimulants, which can cause central nervous system degeneration, interacting with human DNA. These include amphetamine, methamphetamine, 3,4-Methylenedioxymethamphetamine (also known as ecstasy), as well as their main metabolites. The studies were performed through molecular docking and molecular dynamics...