NMA/AGSM/2022/BCS/009 - Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Geraniol, Acyclic Isoprenoid Monoterpene in Ketamine-Induced Psychosis in Mice
Nigerian Medical Journal May 5, 2023 C. Uruaka, O. Georgewill, OU Georgewill
Background Schizophrenia is a chronic neuropsychiatric disease characterized by neurochemical, neurotrophic, and oxido-inflammatory derangements. Geraniol is a neuroactive acyclic isoprenoid monoterpene, which has been reported to demonstrate depressant and antioxidant/anti-inflammatory activities. Herein, we investigated whether geraniol could prevent or reverse ketamine-induced...