Drug Development in Psychiatry: The Long and Winding Road from Chance Discovery to Rational Development.
Advances in neurobiology 2023 Sheldon H. Preskorn
Based extensively on tables and figures, this chapter reviews drug development in psychiatry with an emphasis on antidepressants from the 1950s to the present and then looks forward to the future. It begins with the chance discovery drugs and then moves to through their rational refinement using structure activity relationships to narrow the pharmacological actions of the drugs to those...
DOI: 10.1007/978-3-031-21054-9_1 (opens in new tab)
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Esketamine
Antidepressants
Drug development
Major depression
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